COMPARISON BIOLARVICIDES POTENCIAL OF FRUIT SEEDS AND LEAF PAPAYA EXTRACTS (Carica papaya) ON Aedes aegypti

Authors

  • Fidel Corona Fakultas Kedokteran dan Ilmu Kesehatan Unika Atma Jaya
  • Freggy Spicano Joprang Departemen Parasitologi, Fakultas Kedokteran dan Ilmu Kesehatan Unika Atma Jaya

DOI:

https://doi.org/10.25170/djm.v18i1.2193

Keywords:

Aedes aegypti, biolarvicides, Carica papaya L, papaya leaf, papaya seed

Abstract

Introduction: Aedes aegypti is the major vector of dengue virus. Dengue virus can cause dengue hemorrhagic fever (DHF). DHF is dangerous because it can cause death. World Health Organization (WHO) noted Indonesia as state with the highest dengue cases in Southeast Asia. Effort to control A. aegypti vector that can be done is by using natural substances that have the effect of biolarvicides. This study aims to determine natural biolarvicides potencial of fruit seeds and leaf papaya (Carica papaya) extracts against A. aegypti larvae.


Methods: This study was an experimental study and conducted in 2016 using two groups of samples with the design before and after intervention. Samples were A. aegypti larval instar III and IV with the number of 10 larvaeper concentration and 10 larvae of control for each types of extracts. The concentration used was 0 mg / L (control), 50 mg / L, 100 mg / L, and 150 mg / L for both types of extracts, then observed at 6 hours, 12 hours, 18 hours, and 24 hours after exposure.


Results: This study using Kruskal Wallis test, p value = 0.352. (P> 0.05) means there is no significant difference in the effect of biolarvicides concentration between the two types of extracts that used to the number of dead larvae of A. aegypti.


Conclusion: Fruit seeds and leaf papaya extracts (C. Papaya L.) with concentrations of 50 mg / L, 100 mg/ L, and 150 mg / L are not effective to kill the larvae of A. aegypti. Other studies show concentrations above 21.9 ppm of leaf extract and 442 ppm of fruit seed extract can effectively kill larvae, therefore future studies are needed to determine effective extract concentrations to kill the larvae of A. aegypti.

Downloads

Download data is not yet available.

References

World Health Organization. Dengue and severe dengue. WHO. [cited 2015 Sep 09]. Available from: http://www.who.int/mediacentre/factsheets/fs117/en/.

World Health Organization. Dengue/dengue haemo-rrhagic fever. WHO. [cited 2015 Sep 09]. Available from: http://www.who.int/csr/disease/dengue/en/.

World Health Organization. Dengue vaccine re-search. WHO. [cited 2015 Sep 09]. Available from: http://www.who.int/immunization/research/development/dengue_vaccines/en.

Begum M. Phytochemical and pharmacological investigation of Carica papaya leaf [document on the Internet]. East West University [cited 2015 Sep 09]. Available from:http://dspace.ewubd.edu/han-dle/123456789/685.

Efek larvasida ekstrak etanol daun pepaya (Carica papaya) terhadap larva Aedes aegypti [document on the Internet]. Riau University [cited 2015 Sep 09]. Available from: http://jom.unri.ac.id/index.php/ JOMFDOK/article/viewFile/2850/2765.

Rawani A, Ghosh A, Laskar S, Chandra G. Aliphatic amide from seeds of carica papaya as mosquito larvicide, pupicide, adulticide, repellent and smoke toxicant. J Mosq Res. 2012;2(2):8-18.

Sesanti H, Arsunan AA, Ishak H. Potential test of papaya leaf and seed extract (carica papaya) as larvicides against anopheles mosquito larvae mortality. sp in Jayapura, Papua Indonesia. Int J Sci Res Publ. 2014;4(6).

Hadinegoro SR, Arredondo-García JL, Capeding MR, Deseda C, Chotpitayasunondh T, Dietze R, et al. Efficacy and long-term safety of a dengue vaccine in regions of endemic disease. N Engl J Med. 2015 Sep 24;373(13):1195–206.

Perbandingan metode ekstraksi maserasi dan sokletasi terhadap kadar piperin buah cabe jawa (Piperis retrofracti fruncus) [document on theInternet]. Syarif Hidayahttulah University [cited 2015 Des 1]. Available from: http://repository. uinjkt.ac.id/dspace/bitstream/123456789/24306/1/Istiqomah-fkik.pdf.

Parameter standar umum ekstrak tumbuhan obat [document on the Internet]. Jambi University [cited 2015 Des 1]. Available from: http://putrimayasari. unja.ac.id/?media_dl=16.

Staf Pengajar Departemen Parasitologi FKUI. Buku ajar parasitologi kedokteran. 4th ed. Jakarta: Badan Penerbit FKUI; 2013.

Pictorial keys for the identification of mosquitoes associated with dengue virus transmission [document on the Internet]. [cited 2015 Oct 08]. Available from: http://www.sandfly catalog.org/files/
pdfs/113995-0.pdf .

Key characters for larval Aedes sp. identification [document on the Internet]. California Department of Public Health [cited 2015 Oct 08]. Available from: https://www.cdph.ca.gov/HealthInfo/discond/Documents/AedesLarvalPictureKey.pdf .

Life cycle of mosquito [document on the Internet]. [cited 2015 Oct 08]. Available from: http://www. biologydiscussion.com/experiments/life-cycle-of-mosquito-with-diagram/1754

Centers for Disease Control and Prevention. Mosquito life cycle Dengue. CDC. [cited 2015 Oct 14]. Available from: http://www.cdc.gov/Dengue/ entomologyEcology/m_lifecycle.html

Published

2019-05-05

How to Cite

1.
Corona F, Joprang FS. COMPARISON BIOLARVICIDES POTENCIAL OF FRUIT SEEDS AND LEAF PAPAYA EXTRACTS (Carica papaya) ON Aedes aegypti. DJM [Internet]. 2019 May 5 [cited 2024 Jun. 30];18(1):8-15. Available from: https://ejournal.atmajaya.ac.id/index.php/damianus/article/view/2193
Abstract views: 67 | PDF downloads: 86