• Monica Regina Ngantung Fakultas Kedokteran dan Ilmu Kesehatan Unika Atma Jaya
  • Rita Dewi Departemen Biokimia – Kimia, Fakultas Kedokteran dan Ilmu Kesehatan Unika Atma Jaya
  • Jojor Lamsihar Manalu Departemen Fisiologi – Fisika, Fakultas Kedokteran dan Ilmu Kesehatan Unika Atma Jaya
Keywords: hyperlipidemia, green tea, black tea


Introduction: Hyperlipidemia is the cause of 18% of cardiovascular disease and 56% of ischemic heart disease worldwide. According to the World Health Organization (WHO), in 2017, cardiovascular disease is the leading cause of death worldwide. In its role against cardiovascular disease, green tea and black tea can be used as an alternative treatment in reducing triglyceride levels.
Methods: This study is an in vivo experimental. This experiment using 16 Rattus norvegicus rats strain Sprague-Dawley induced with lard and raw quail egg yolk before and divided into two groups; green tea and black tea groups. Treatment is carried out for 17 days and checking the triglyceride level before and after intervention using test strip and tools from Lipid Pro. Data were collected and analyzed using the Shapiro-Wilk test, paired t-test, and unpaired t-test.                                                                                                                                                              Results: The results showed that the data were normally distributed (Shapiro-Wilk test p> 0.05). Treatment with green tea and black tea for 17 days led to a significant drop in triglyceride level (paired t-test p <0.05), and there is a significant difference between the effectiveness of the intervention group (unpaired t-test p <0.05).
Conclusion: There was a significant decrease in rats’ triglyceride levels in the administration of green tea and black tea, and green tea is more effective than black tea in reducing triglyceride levels on hyperlipidemic Rattus Norvegicus.


Download data is not yet available.


Anwar T. Dislipidemia sebagai faktor risiko penyakit jantung koroner [Internet]. Repository.usu.ac.id. 2004. Terdapat pada: https://www.researchgate.net/publication/42321431_Dislipidemia_Sebagai_Faktor_Resiko_Penyakit_Jantung_Koroner

Arief M, Novriansyah R, Tjeng Budianto I, Bimo HarHarmaji M. Potensi bunga karamunting (Melas-toma malabathricum L.) terhadap kadar kolesterol total dan trigliserida pada tikus putih jantan hiperlipidemia yang diinduksi propiltiourasil. Journal Prestasi [Internet]. 2013;1(2). Terdapat pada: http://ejournal.unlam.ac.id/index.php/prestasi/ article/view/268

Cardiovascular diseases (CVDs) [Internet]. 2017 [dikutip 1 April 2018]. Terdapat pada: http://who.int/mediacentre/factsheests/fs317/en/

Overview [Internet]. World Bank. 2018 [dikutip 2 April 2018]. Terdapat pada: http://www.worldbank. org/en/country/indonesia/overview

Riskesdas 2013 [Internet]. Depkes.go.id. 2013 [dikutip 2 April 2018]. Terdapat pada:http://www. depkes.go.id/resources/download/general/Hasil%20Riskesdas%202013.pdf

Side effects [Internet]. nhs.uk. 2019 [dikutip 12 January 2019]. Terdapat pada: https://www.nhs.uk/ conditions/statins/side-effects/

Syah A. Taklukkan penyakit dengan teh hijau. Jakarta: Agro Media Pustaka; 2006.

Shrestha S, Ehlers S, Lee J, Fernandez M, Koo S. Dietary green tea extract lowers plasma and hepatic trigliserida and decreases the expression of sterol regulatory element-binding protein-1c mRNA and its responsive genes in fructose-fed, ovariectomized rats. The Journal of Nutrition. 2009;139(4):640-645.

Bahorun T, Luximon-Ramma A, Neergheen-Bhujun V, Gunness T, Googoolye K, Auger C, et al. The effect of black tea on risk factors of cardiovascular disease in a normal population. Preventive Medicine. 2012;54:S98-S102.

Yung LM, Leung FP, Wong WT, Tian XY, Yung LH,Chen ZY, et al. Tea polyphenols benefit vascular function. Inflammopharmacol. 2008 Oct 1;16(5): 230–4.

Alshatwi A, Al Obaaid M, Al Sedairy S, Ramesh E, Lei K. Black and green tea improves lipid profile and lipid peroxidation parameters in Wistar rats fed a high-cholesterol diet. Journal of Physiology and Biochemistry. 2010;67(1):95-104.

Jochmann N, Lorenz M, Krosigk A von, Martus P, Böhm V, Baumann G, et al. The efficacy of black tea in ameliorating endothelial function is equivalent to that of green tea. British Journal of Nutrition. 2008 Apr;99(4):863–8.

Dewi K. Pengaruh ekstrak teh hijau (Camellia Sinensis var. Assamica) terhadap penurunan berat badan, kadar trigliserida dan kolesterol total pada tikus jantan galur Wistar. JKM [Internet]. 2008 [dikutip 15 October 2018];7(2):155-162. Terdapat pada: http://repository.maranatha.edu/3368/1/Pengaruh%20Ekstrak%20Teh%20Hijau.pdf

Hamdaoui M, Snoussi C, Dhaouadi K, Fattouch S, Ducroc R, Le Gall M, et al. Tea decoctions prevent body weight gain in rats fed high-fat diet; black tea being more efficient than green tea. Journal of Nutrition & Intermediary Metabolism [Internet]. 2016;6:33-40. Terdapat pada: https://www.science direct.com/science/article/pii/S2352385915300323

Khanam P. Lipid and cholesterol lowering effect of green vs black tea - how much, how frequent: A literature review. International Journal for Innovative Research in Multidisciplinary Field [Internet]. 2016 [dikutip 10 November 2019];2(10):167-175. Terdapat pada: https://pdfs. semanticscholar.org/1500/1dde6b09cf5eb06737dea697e09e044e46d9
How to Cite
Ngantung M, Dewi R, Manalu J. EFFECTIVITY COMPARISON BETWEEN GREEN TEA AND BLACK TEA ON LOWERING TRIGLYCERIDE LEVELS IN HYPERLIPIDEMIA ANIMAL MODEL [Internet]. Damianus Journal of Medicine [Internet]. 27Nov.2020 [cited 25Feb.2021];19(2):118 -24. Available from: http://ejournal.atmajaya.ac.id/index.php/damianus/article/view/1225
Abstract viewed = 0 times
PDF (Bahasa Indonesia) downloaded = 0 times