Correlation of serum albumin to muscle mass, muscle strength, and physical performance in elderly

Authors

  • Nur Riviati University of Sriwijaya
  • Legiran FK Univ. Sriwijaya
  • Irsan Saleh FK Univ. Sriwijaya
  • Taufik Indrajaya FK Univ. Sriwijaya
  • Surya Dharma FK Univ. Sriwijaya
  • Muhammad Reagen FK Univ. Sriwijaya
  • Fifi Yuniarti FK Univ. Sriwijaya
  • Syafran Rasidi FK Univ. Sriwijaya
  • Fadhyl Zuhry Lubis FK Univ. Sriwijaya
  • Bima Indra FK Univ. Sriwijaya

DOI:

https://doi.org/10.25170/djm.v22i1.4233

Keywords:

albumin, muscle mass, muscle strength, physical performance, sarcopenia

Abstract

Introduction: Sarcopenia is a common problem found in the elderly. It is characterized by loss of muscle mass, muscle strength, and/or low physical performance. Currently, there’s little research on the association between serum albumin and muscle mass, muscle strength, and physical performance in the elderly, especially in Indonesia. This study aimed to find the correlation between serum albumin and muscle mass, muscle strength, and physical performance in the elderly.

Method: A cross-sectional study was conducted from July 2022 to December 2022 towards elderly patients (>60 years) from the geriatric polyclinic at RSUP Moh. Hoesin Palembang. Serum albumin was examined for its correlation with muscle mass, muscle strength, and physical performance using Spearman’s test.

Result: 41 elderly patients were included in this study (mean age 70.75 ± 7 years, 56.1% women). Correlation analysis showed that there’s a significant positive correlation between serum albumin with muscle strength (r=0.354, p=0.012) and a negative correlation with physical performance (r=-0.5, p <0.001). In comparison, there was no significant correlation between serum albumin and muscle mass (r=- 0.05, p=0.367).

Conclusion: Muscle strength and physical performance have a significant correlation with serum albumin in the elderly. Therefore, even in the normal range, lower serum albumin is closely related to sarcopenia in the elderly.

Key Words: albumin, muscle mass, muscle strength, physical performance, sarcopenia.

Downloads

Download data is not yet available.

References

Pangiribowo S, Hardhana Boga, Widiantini W, Habibi H. Infodatin: Lansia berdaya, bangsa sejahtera. Pusdatin. 2022;1–12.

Chen LK, Woo J, Assantachai P, Auyeung TW, Chou MY, Iijima K, et al. Asian working group for sarcopenia: 2019 Consensus update on sarcopenia diagnosis and treatment. J Am Med Dir Assoc [Internet]. 2020 Mar 1 [cited 2023 Jan 29];21(3):300-307.e2. Available from: https://pubmed.ncbi.nlm.nih.gov/32033882/

van Ancum JM, Tuttle CSL, Koopman R, Pijnappels M, Meskers CGM, Paul SK, et al. Albumin and C-reactive protein relate to functional and body composition parameters in patients admitted to geriatric rehabilitation after acute hospitalization: findings from the RESORT cohort. Eur Geriatr Med. 2022 Jun 1;13(3):623–32.

Li X, Cao X, Ying Z, Zhang J, Sun X, Hoogendijk EO, et al. Associations of Serum Albumin With Disability in Activities of Daily Living, Mobility and Objective Physical Functioning Regardless of Vitamin D: Cross-Sectional Findings From the Chinese Longitudinal Healthy Longevity Survey. Front Nutr. 2022 Feb 24;9.

Hwang J, Park S. Gender-Specific Risk Factors and Prevalence for Sarcopenia among Community-Dwelling Young-Old Adults. Int J Environ Res Public Health. 2022 Jun 1;19(12).

Reijnierse EM, Trappenburg MC, Leter MJ, Sipilä S, Stenroth L, Narici M v., et al. Serum albumin and muscle measures in a cohort of healthy young and old participants. Age (Omaha). 2015 Oct 28;37(5).

Ilmiah J, Medisia M, Zainoel A, Banda A. The Relationship of Serum Albumin Levels with Handgrip Strength on Cancer Patients in RSUD dr [Internet]. Vol. 2. 2017. Available from: http://jim.unsyiah.ac/medisia

Yamamoto M, Adachi H, Enomoto M, Fukami A, Nakamura S, Nohara Y, et al. Lower albumin levels are associated with frailty measures, trace elements, and an inflammation marker in a cross-sectional study in Tanushimaru. Environ Health Prev Med. 2021 Dec 1;26(1).

Kwon J, Suzuki T, Yoshida H, Kim H, Yoshida Y, Iwasa H. Concomitant lower serum albumin and vitamin D levels are associated with decreased objective physical performance among Japanese community-dwelling elderly. Gerontology. 2007 Aug;53(5):322–8.

Uemura K, Doi T, Lee S, Shimada H. Sarcopenia and low serum albumin level synergistically in-crease the risk of incident disability in older adults. J Am Med Dir Assoc. 2019 Jan 1;20(1):90–3.

Snyder CK, Lapidus JA, Cawthon PM, Dam TTL, Sakai LY, Marshall LM. Serum albumin in relation to change in muscle mass, muscle strength, and muscle power in older men. J Am Geriatr Soc. 2012 Sep;60(9):1663–72.

Astiyani RF. Pengaruh kadar albumin dan skor MNA terhadap massa otot pada pasien lansia dengan Diabetes Melitus. 2019.

Riviati N, Setiati S, Laksmi PW, Abdullah M. Factors related with handgrip strength in elderly patients. Vol. 49, Acta Med Indones-Indones J Intern Med •. 2017.

Downloads

Published

2023-07-04

How to Cite

1.
Riviati N, Legiran, Saleh I, Indrajaya T, Dharma S, Reagen M, Yuniarti F, Rasidi S, Lubis FZ, Indra B. Correlation of serum albumin to muscle mass, muscle strength, and physical performance in elderly. DJM [Internet]. 2023 Jul. 4 [cited 2024 Nov. 24];22(1):21-7. Available from: https://ejournal.atmajaya.ac.id/index.php/damianus/article/view/4233
Abstract views: 367 | PDF downloads: 257