Hubungan fungsi kognitif spesifik terhadap risiko frailty pada lansia

Authors

  • Carissa Marvella Budhy Universitas Katolik Indonesia Atma Jaya
  • Yuda Turana Universitas Katolik Indonesia Atma Jaya
  • Yvonne Suzy Handajani Universitas Katolik Indonesia Atma Jaya
  • Kevin Kristian Universitas Katolik Indonesia Atma Jaya

DOI:

https://doi.org/10.25170/djm.v24i3.6155

Keywords:

frailty, fungsi kognitif, lansia, usia

Abstract

Pendahuluan: Penuaan populasi menyebabkan beban kesehatan meningkat, salah satunya adalah frailty. Berdasarkan systematic review dan meta-analysis pada 2023 prevalensi frailty pada lansia di Indonesia adalah 26,8%, sedangkan 55,5% mengalami pre-frail. Penelitian ini bertujuan untuk memeroleh gambaran tentang frailty serta faktor risikonya di Pusaka Kebon Jeruk, Jakarta Barat.

Metode: Penelitian ini menggunakan rancangan potong-lintang dan melibatkan 100 responden berusia ≥60 tahun. Pengumpulan data dilakukan melalui wawancara dengan menggunakan, seperti Fried Fraily Index, MoCA-Ina, dan CERAD-NB. Analisis data dilakukan dengan metode chi-square dan multiple logistic regression.

Hasil: Dari 100 responden, terdapat 75 (75% subjek) berusia 60-74 tahun dengan rerata usia 70,13 tahun, perempuan (71%), durasi pendidikan ≥12 tahun (90%). Terdapat 18 (18% subjek) lansia yang mengalami frailty. Analisis bivariat menunjukkan bahwa faktor yang memiliki hubungan signifikan adalah usia (p: <0,001; RO: 7,633; 95%CI: 2,519 – 23,127) dan constructional praxis (p: 0,037; RO: 3,162; 95%CI: 1,032 – 9,685).

Simpulan: Frailty memiliki hubungan bermakna dengan usia dan fungsi kognitif constructional praxis. Dengan usia menjadi faktor yang paling memengaruhi dan meningkatkan risiko frailty pada lansia.

Downloads

Download data is not yet available.

References

1. Veronese N, editor. Frailty and cardiovascular diseases: research into an elderly population. Cham: Springer; 2020.

2. Hoogendijk EO, Afilalo J, Ensrud KE, Kowal P, Onder G, Fried LP. Frailty: Implications for clinical practice and public health. The Lancet. Oktober 2019;394 (10206):1365–75.

3. Pradana AA, Chiu HL, Lin CJ, Lee SC. Prevalence of frailty in Indonesia: A systematic review and meta-analysis. BMC Geriatr. 27 November 2023; 23(1):778.

4. Vahedi A, Eriksdotter M, Ihle‐Hansen H, Wyller TB, Øksengård AR, Fure B. Cognitive impairment in people with physical frailty using the phenotype model: A systematic review and meta analysis. Int J Geriatr Psychiatry. Nov 2022;37(11):gps.5822.

5. Wang X, Hu J, Wu D. Risk factors for frailty in older adults. Medicine (Baltimore). 26 Agustus 2022;101 (34):e30169.

6. Kong LN, Lyu Q, Yao HY, Yang L, Chen SZ. The prevalence of frailty among community-dwelling older adults with diabetes: A meta-analysis. Int J Nurs Stud. Juli 2021;119:103952.

7. Gale CR, Cooper C, Sayer AA. Framingham cardiovascular disease risk scores and incident frailty: the English longitudinal study of ageing. AGE. Agustus 2014;36(4):9692.

8. Basrowi RW, Rahayu EM, Khoe LC, Wasito E, Sundjaya T. The road to healthy ageing: What has Indonesia achieved so far? Nutrients. 28 September 2021;13(10):3441.

9. Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, et al. Frailty in older adults: Evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 1 Maret 2001;56(3):M146–57.

10. Dautzenberg G, Lijmer J, Beekman A. Diagnostic accuracy of the Montreal Cognitive Assessment (MoCA) for cognitive screening in old age psychiatry: Determining cutoff scores in clinical practice. Avoiding spectrum bias caused by healthy controls. Int J Geriatr Psychiatry. Maret 2020;35(3): 261–9.

11. Paajanen T, Hänninen T, Tunnard C, Hallikainen M, Mecocci P, Sobow T, et al. CERAD Neuro-psychological compound scores are accurate in detecting prodromal Alzheimer’s Disease: A prospective AddNeuroMed study. J Alzheimers Dis. 7 Februari 2014;39(3):679–90.

12. Petersmann A, Müller-Wieland D, Müller UA, Landgraf R, Nauck M, Freckmann G, et al. Definition, classification and diagnosis of diabetes mellitus. Exp Clin Endocrinol Diabetes. Desember 2019;127(S 01):S1–7.

13. National Cholesterol Education Program. Detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). National Institutes of Health; 2001.

14. Gordon EH, Hubbard RE. Frailty: Understanding the difference between age and ageing. Age Ageing. 2 Agustus 2022;51(8):afac185.

15. Setiati S, Laksmi PW, Aryana IGPS, Sunarti S, Widajanti N, Dwipa L, et al. Frailty state among Indonesian elderly: Prevalence, associated factors, and frailty state transition. BMC Geriatr. Desember 2019;19(1):182.

16. Mangin D, Lawson J, Risdon C, Siu HYH, Packer T, Wong ST, et al. Association between frailty, chronic conditions and socioeconomic status in community-dwelling older adults attending primary care: A cross-sectional study using practice-based research network data. BMJ Open. 2023;13(2): e066269.

17. Park C, Ko FC. The science of frailty. Clin Geriatr Med. November 2021;37(4):625–38.

18. Brigola AG, Alexandre TDS, Inouye K, Yassuda MS, Pavarini SCI, Mioshi E. Limited formal education is strongly associated with lower cognitive status, functional disability and frailty status in older adults. Dement Neuropsychol. Juni 2019;13(2):216–24.

19. Fabrício DDM, Chagas MHN, Diniz BS. Frailty and cognitive decline. Transl Res. Juli 2020;221:58–64.

20. Ma L, Chan P. Understanding the physiological links between physical frailty and cognitive decline. Aging Dis. 2020;11(2):405.

21. Chen S, Honda T, Narazaki K, Chen T, Kishimoto H, Haeuchi Y, et al. Physical frailty is associated with longitudinal decline in global cognitive function in non-demented older adults: A prospective study. J Nutr Health Aging. Januari 2018;22(1):82–8.

22. Jung H, Kim M, Lee Y, Won CW. Prevalence of physical frailty and its multidimensional risk factors in Korean community-dwelling older adults: Findings from Korean Frailty and Aging Cohort Study. Int J Environ Res Public Health. 2020 Nov 1;17(21):7883.

23. Suzy Handajani Y, Widjaja N, Turana Y. Associations between specific performance cognitive function with frailty of elderly peoples in urban Jakarta, Indonesia. Aging Med Healthc. 24 Maret 2020;11(1):20–6.

24. Quental NBM, Brucki SMD, Bueno OFA. Visuo-spatial function in early Alzheimer’s disease: the use of the Visual Object and Space Perception (VOSP) battery. PLoS One. 2013 Jul 16;8(7): e68398.

25. Nemoto M, Sasai H, Yabushita N, Tsuchiya K, Hotta K, Fujita Y, et al. A novel exercise for enhancing visuospatial ability in older adults with frailty: Development, feasibility, and effectiveness. Geriatrics. 3 Mei 2020;5(2):29.

26. Chen S, Honda T, Narazaki K, Chen T, Nofuji Y, Kumagai S. Global cognitive performance and frailty in non-demented community-dwelling older adults: findings from the Sasaguri Genkimon Study. Geriatr Gerontol Int. 2016 Jun;16(6):729–36.

27. Gale C, Ritchie SJ, Starr JM, Deary IJ. Physical frailty and decline in general and specific cognitive abilities: the Lothian Birth Cohort 1936. J Epidemiol Community Health. 2020 Feb;74(2):108-13.

28. Kim S, Jung HW, Won CW. What are the illnesses associated with frailty in community-dwelling older adults: the Korean Frailty and Aging Cohort Study. Korean J Intern Med. 1 Juli 2020;35(4):1004–13.

29. Howrey BT, Al Snih S, Markides KS, Ottenbacher KJ. Frailty and diabetes among Mexican American older adults. Ann Epidemiol. Juli 2018;28(7):421-426.e1.

30. Yin M, Zhang X, Zheng X, Chen C, Tang H, Yu Z, et al. Cholesterol alone or in combination is associated with frailty among community-dwelling older adults: A cross-sectional study. Exp Gerontol. September 2023;180:112254.

Published

2025-12-30

How to Cite

1.
Budhy CM, Turana Y, Handajani YS, Kristian K. Hubungan fungsi kognitif spesifik terhadap risiko frailty pada lansia. DJM [Internet]. 2025 Dec. 30 [cited 2026 Jan. 29];24(3):194-202. Available from: https://ejournal.atmajaya.ac.id/index.php/damianus/article/view/6155

Most read articles by the same author(s)